Tuflux® Silicone and TPE Tubing | Sartorius (2024)

Liquid transfer is an essential part of biomanufacturing processes. With Tuflux® tubing,benefit from low extractable profiles for both silicone and TPEtubing to transfercritical fluids across all process steps.

A Broad Range of Tubing Standards

Tuflux® tubes are available in standard dimensions from 1/8" (3.2 mm) to 1" (25.4 mm) for the internal dimensions and a wall thickness from 1.6 mm to 4.8 mm. These tubes’ function both as non-sterile standalone coils to build your own assemblies and as part of pre-sterilized single-use systems from Sartorius, which include bags, transfer sets, filters, or bioreactors.

There are three types of Tuflux® tubes, the table below will help you assess which one is best suited for your process need:

Attributes

Tuflux® SILTuflux® TPE

Tuflux® SIL Braided

Sealable | weldable

No

Yes

No

Recommended for pumping

Yes

Yes*

No

Recommended for high pressure

No

No

Yes

Standard dimensions available from stock (IDxOD)

1/8" x 1/4" (3.2 x 6.4 mm)
1/4" x 3/8" (6.4 x 9.5 mm)
1/4" x 7/16" (6.4 x 11.1 mm)
3/8" x 5/8" (9.5 x 15.9 mm)
1/2" x 3/4" (12.7 x 19.1 mm)
3/4" x 1" (19.1 x 25.4 mm)
3/4" x 1-1/8" (19.1 x 28.6 mm)

1/8" x 0.355"
(3.2 x 9 mm)
1/4" x 1/2"
(6.4 x 12.7 mm)
3/8" x 5/8"
(9.5 x 15.9 mm)
1/2" x 7/8"
(12.7 x 19.1 mm)
3/4" x 1-1/8"
(19.1 x 28.6 mm)
1" x 1-3/8"
(25.4 x 34.9 mm)

Extractable guide | validation guide

Yes | Yes

Yes | Yes

Yes | Yes

Dimensional color coding

No

Yes (YL, OR, RD, WH, GY, BL, BK)

No

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*for light pumping applications

Process Ready Pumping Performance

Tuflux® Silicone and TPE Tubing | Sartorius (1)

Tuflux® SIL Silicone Tubing

Tuflux® SIL is designed to facilitate fluid transfer in biopharmaceutical manufacturing processes. Tuflux® SIL is a highly resistant platinum-cured silicone tubing manufactured by Raumedic.

  • Low extractable profile
  • Resistant to pumping
  • Easy handling

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Low Extractable Profile

Low Extractable Profile

Tuflux® Silicone and TPE Tubing | Sartorius (2)

Purity and Cleanliness

Benefit from a silicone tubing with a low extractable profile for the transfer of critical fluids. Sartorius’ platinum-cured silicone tubing undergoes an extensive post-curing process after extrusion to create a product with extremely low levels of siloxanes, the most relevant extractable group within silicone products. Tuflux® SIL tubing is manufactured in ISO 7 cleanrooms to maintain the cleanliness of the drug substances it carries.

Resistant to Pumping

Resistant to Pumping

Tuflux® Silicone and TPE Tubing | Sartorius (3)

Robust Tubing

Tuflux® SIL tubing's hardness of 60 Shore A combined with an optimized wall thickness dedicated per size ensures a solid compromise between pressure resistance and long pump life with high flow rates. Tuflux® SIL has been designed to prevent kinking but maintain enough flexibility for efficient operator handling.

Easy Handling

Easy Handling

Tuflux® Silicone and TPE Tubing | Sartorius (4)

Proprietary Low Tack Treatment

Tuflux® SIL undergoes a surface treatment in a plasma process that reduces the stickiness of the surface when compared to non-surface treated silicone tubing products. This eases the unwinding of coils, as well as handling in general.

More Than Just Another TPE Tubing

Tuflux® Silicone and TPE Tubing | Sartorius (5)

Tuflux® TPE Thermoplastic Elastomer Tubing

Tuflux® TPE has been designed specifically for liquid transfer in the biopharmaceutical industry. It can be heat sealed and welded with Biosealer® TC and Biowelder® TC to maintain sterile conditions.

  • Ease of use/Error proofing
  • Cell-growth compatibility
  • High flexibility for use with other materials

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Color-Coding

Color-Coding

Tuflux® Silicone and TPE Tubing | Sartorius (6)

Mitigate Errors with Embedded Colors

The unique color-coding of Tuflux® TPE tubing aligns with the Biowelder® TC tube holders. In addition, the printing of the inner and outer diameter dimensions, as well as the tube material, facilitates identification and ease of use and mitigates operator errors.

Cell Growth

Cell Growth

Tuflux® Silicone and TPE Tubing | Sartorius (7)

Tubing Optimized for Cell Growth

Tuflux® TPE has been specifically designed to be compatible with cell growth. Indeed, its antioxidant levels have been optimized in order to prevent any risk of toxicity caused by the presence of bis(2,4-di-tert-butylphenlyl) phosphate (bDtBPP). As a result, cell growth is not inhibited even under worst-case surface-to-volume ratios in small-scale applications.

Co-Welding

Co-Welding

Tuflux® Silicone and TPE Tubing | Sartorius (8)

Co-welding With Other TPE Tubing

Co-welding between Tuflux® TPE and different TPE tubes is possible thanks to Biowelder® TC. Indeed co-welding parameters have been validated for different combinations of gamma-irradiated and/or autoclaved tubes.

High Pressure Resistance Tubing

Tuflux® Silicone and TPE Tubing | Sartorius (9)

Tuflux® SIL Braided

Braided Tuflux® SIL is the newest product in the Sartorius tubing portfolio. Its composition is identical to Tuflux® SIL just with an integrated mesh.

  • High pressure resistance
  • Medical grade PET mesh
  • Full validation package for easy adoption

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Pressure Resistance

Pressure Resistance

Tuflux® Silicone and TPE Tubing | Sartorius (10)

Pressure Resistance

Braided Tuflux® SIL is made of the same silicone as Tuflux® SIL and therefore benefits from the same advantages: low extractable profiles, a good compromise between strength and flexibility and a low tack treatment to reduce surface stickiness. It is reinforced with a mesh, enabling it to be resistant to pressures up to 60 bar.

Medical Grade Mesh

Medical Grade Mesh

Tuflux® Silicone and TPE Tubing | Sartorius (11)

Medical Grade Mesh

Braided Tuflux® SIL is reinforced with a medical grade PET mesh material which enables high pressure resistance while ensuring that your fluids are kept safe.

Fully Validated

Fully Validated

Related Products

Biowelder® Total Containment (TC) and Biosealer® TC provide innovative solutions to complement your Tuflux® TPE system.

Tuflux® Silicone and TPE Tubing | Sartorius (12)

Biowelder®TC Sterile Tube Welding Device

The Biowelder® TC is anautomated device for connecting thermoplastic tubing in a sterile welding operation.

Explore Biowelder® TC

Tuflux® Silicone and TPE Tubing | Sartorius (13)

Biosealer®TC Aseptic Tube Sealing Device

The Biosealer® TC is a robust, flexible and easy-to-use device that generates sterile TPE tubing disconnections.

ExploreBiosealer® TC

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Related Assets

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Application Note

Tuflux® SIL Tubing (Sartorius) vs Pharma-50 (Dow Corning)

PDF | 545.9 KB

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Tuflux® Silicone and TPE Tubing | Sartorius (15)

Application Note

Long Term Pumping Assessment With Tuflux® SIL

PDF | 345.3 KB

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Tuflux® Silicone and TPE Tubing | Sartorius (16)

Product Guide

Braided Tuflux® SIL (Sartorius) vs Sani-Tech® STHT®-R (Saint-Gobain)

PDF | 1.2 MB

Download

Tuflux® Silicone and TPE Tubing | Sartorius (17)

Product Guide

Tuflux® TPE Tubing (Sartorius) vs C-Flex® 374 (Saint-Gobain)

PDF | 288.7 KB

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Consult Our Experts

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